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keywords Genetics of diabetes
overview Dr. Bell's research program focuses on the genetics of diabetes and other metabolic disorders.
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Concept Alleles
Concept Amino Acid Sequence
Concept Analysis of Variance
Concept Base Sequence
Concept Genetic Vectors
Concept DNA Mutational Analysis
Concept DNA, Recombinant
Concept Genes, Regulator
Concept Cost-Benefit Analysis
Concept Genes, Dominant
Concept Genes
Concept Genes, Bacterial
Concept Genetic Complementation Test
Concept Multigene Family
Concept Genetics, Population
Concept Models, Molecular
Concept Models, Genetic
Concept Molecular Sequence Data
Concept Molecular Weight
Concept Repetitive Sequences, Nucleic Acid
Concept Molecular Biology
Concept Major Histocompatibility Complex
Concept Selection, Genetic
Concept Polymorphism, Genetic
Concept Pseudogenes
Concept Genetic Markers
Concept Hybridization, Genetic
Concept Regression Analysis
Concept Sequence Homology, Nucleic Acid
Concept Genes, ras
Concept Cluster Analysis
Concept Transcription, Genetic
Concept Sequence Homology, Amino Acid
Concept Genetic Variation
Concept Leukemia, Myeloid
Concept Gene Library
Concept RNA Splice Sites
Concept Genes, Tumor Suppressor
Concept Genes, Wilms Tumor
Concept Molecular Probes
Concept Genomic Library
Concept Sequence Analysis, DNA
Concept Genes, Reporter
Concept Consensus Sequence
Concept Evolution, Molecular
Concept Transgenes
Concept Genetic Association Studies
Concept Exome
Concept Oligonucleotide Array Sequence Analysis
Concept Genetic Diseases, Inborn
Concept Animals, Genetically Modified
Concept Promoter Regions, Genetic
Concept Regulatory Elements, Transcriptional
Concept Multivariate Analysis
Concept Survival Analysis
Concept Genetic Therapy
Concept Genome, Human
Concept Antisense Elements (Genetics)
Concept Genes, src
Concept Metabolic Networks and Pathways
Concept Transcriptome
Concept Cloning, Molecular
Concept Crosses, Genetic
Concept Enhancer Elements, Genetic
Concept Epistasis, Genetic
Concept Genes, Fungal
Concept Genetic Testing
Concept Genetic Linkage
Concept Translocation, Genetic
Concept Conserved Sequence
Concept Directed Molecular Evolution
Concept Genetic Predisposition to Disease
Concept Polymorphism, Single Nucleotide
Concept Protein Array Analysis
Concept Quantitative Trait Loci
Concept Epigenesis, Genetic
Concept Genetic Loci
Academic Article Sequence and functional characterization of a third inositol trisphosphate receptor subtype, IP3R-3, expressed in pancreatic islets, kidney, gastrointestinal tract, and other tissues.
Academic Article Human glucagon-like peptide-1 receptor gene. Localization to chromosome band 6p21 by fluorescence in situ hybridization and linkage of a highly polymorphic simple tandem repeat DNA polymorphism to other markers on chromosome 6.
Academic Article Pharmacological properties of two cloned somatostatin receptors.
Academic Article Cloning and functional comparison of kappa and delta opioid receptors from mouse brain.
Academic Article Hormonal/metabolic regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice.
Academic Article Candidate gene studies in pedigrees with maturity-onset diabetes of the young not linked with glucokinase.
Academic Article Human insulin receptor substrate-1 gene (IRS1): chromosomal localization to 2q35-q36.1 and identification of a simple tandem repeat DNA polymorphism.
Academic Article cDNA sequence and localization of polymorphic human cytosolic phosphoenolpyruvate carboxykinase gene (PCK1) to chromosome 20, band q13.31: PCK1 is not tightly linked to maturity-onset diabetes of the young.
Academic Article Identification of a simple tandem repeat DNA polymorphism in the human glycogen synthase gene and linkage to five markers on chromosome 19q.
Academic Article Human GLUT4/muscle-fat glucose-transporter gene. Characterization and genetic variation.
Academic Article Linkage and association studies in insulin-dependent diabetes with a new dinucleotide repeat polymorphism at the GAD65 locus.
Academic Article Human hexokinase II gene: exon-intron organization, mutation screening in NIDDM, and its relationship to muscle hexokinase activity.
Academic Article Sequence of human hexokinase III cDNA and assignment of the human hexokinase III gene (HK3) to chromosome band 5q35.2 by fluorescence in situ hybridization.
Academic Article Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance.
Academic Article Chromosomal assignment and tissue distribution of novel expressed sequence tags from a human pancreatic islet cDNA library.
Academic Article Characterization of a third simple tandem repeat polymorphism in the human glucokinase gene.
Academic Article Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms.
Academic Article Rat inwardly rectifying potassium channel Kir6.2: cloning electrophysiological characterization, and decreased expression in pancreatic islets of male Zucker diabetic fatty rats.
Academic Article Exclusion of epidermal growth factor and high-resolution physical mapping across the Rieger syndrome locus.
Academic Article Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)
Academic Article Identification of microsatellite markers near the human genes encoding the beta-cell ATP-sensitive K+ channel and linkage studies with NIDDM in Japanese.
Academic Article Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)
Academic Article Detection of a polymorphism within the pepsinogen C gene with PCR: construction of a linkage map around PGC from 6p11-6p21.3.
Academic Article Mutations in the hepatocyte nuclear factor-1alpha gene in MODY and early-onset NIDDM: evidence for a mutational hotspot in exon 4.
Academic Article Searching for NIDDM susceptibility genes: studies of genes with triplet repeats expressed in skeletal muscle.
Academic Article Cloning and characterization of exodus, a novel beta-chemokine.
Academic Article Molecular analysis of the fructose transporter gene (GLUT5) in isolated fructose malabsorption.
Academic Article MODY: a model for the study of the molecular genetics of NIDDM.
Academic Article Increased expression of endothelin B receptor mRNA following subarachnoid hemorrhage in monkeys.
Academic Article Human Oct3 gene family: cDNA sequences, alternative splicing, gene organization, chromosomal location, and expression at low levels in adult tissues.
Academic Article Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12.
Academic Article Identification of nine novel mutations in the hepatocyte nuclear factor 1 alpha gene associated with maturity-onset diabetes of the young (MODY3).
Academic Article Genetic variation in the hepatocyte nuclear factor-1 alpha gene in Danish Caucasians with late-onset NIDDM.
Academic Article Maturity onset diabetes of the young (MODY).
Academic Article An approach for identifying simple sequence repeat DNA polymorphisms near cloned cDNAs and genes. Linkage studies of the islet amyloid polypeptide/amylin and liver glycogen synthase genes and NIDDM.
Academic Article Linkage studies in NIDDM with markers near the sulphonylurea receptor gene.
Academic Article Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus.
Academic Article Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.
Academic Article Studies of association between the gene for calpain-10 and type 2 diabetes mellitus in the United Kingdom.
Academic Article Mutations in the coding region of the neurogenin 3 gene (NEUROG3) are not a common cause of maturity-onset diabetes of the young in Japanese subjects.
Academic Article Linkage analysis of maturity-onset diabetes of the young with microsatellite polymorphisms. No linkage to ADA or GLUT2 genes in two families.
Academic Article beta-cell transcription factors and diabetes: no evidence for diabetes-associated mutations in the gene encoding the basic helix-loop-helix transcription factor neurogenic differentiation 4 (NEUROD4) in Japanese patients with MODY.
Academic Article Expression and regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice.
Academic Article A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance.
Academic Article Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young.
Academic Article Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome.
Academic Article Functional properties of the R154X HNF-4alpha protein generated by a mutation associated with maturity-onset diabetes of the young, type 1.
Academic Article Identification of three missense mutations in the peroxisome proliferator-activated receptor alpha gene in Japanese subjects with maturity-onset diabetes of the young.
Academic Article Reduced skeletal muscle calpain-10 transcript level is due to a cumulative decrease in major isoforms.
Academic Article No diabetes-associated mutations in the coding region of the hepatocyte nuclear factor-4gamma gene (HNF4G) in Japanese patients with MODY.
Academic Article Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome.
Academic Article Diabetes mellitus and genetically programmed defects in beta-cell function.
Academic Article Variation within the type 2 diabetes susceptibility gene calpain-10 and polycystic ovary syndrome.
Academic Article Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians.
Academic Article Genetic variants of hepatocyte nuclear factor-1beta in Chinese young-onset diabetic patients with nephropathy.
Academic Article Association of the calpain-10 gene with type 2 diabetes mellitus in a Mexican population.
Academic Article Control of pancreas and liver gene expression by HNF transcription factors.
Academic Article Structure and transcription of the human m3 muscarinic receptor gene.
Academic Article Geographic and haplotype structure of candidate type 2 diabetes susceptibility variants at the calpain-10 locus.
Academic Article Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells.
Academic Article Genome-wide scan for metabolic syndrome and related quantitative traits in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25.
Academic Article Mapping genes influencing type 2 diabetes risk and BMI in Japanese subjects.
Academic Article Genome-wide scan for type 2 diabetes loci in Hong Kong Chinese and confirmation of a susceptibility locus on chromosome 1q21-q25.
Academic Article Dual promoter structure of ZFP106: regulation by myogenin and nuclear respiratory factor-1.
Academic Article Optical imaging of pancreatic beta cells in living mice expressing a mouse insulin I promoter-firefly luciferase transgene.
Academic Article Meta-analysis and a large association study confirm a role for calpain-10 variation in type 2 diabetes susceptibility.
Academic Article Anti-diabetic effect of ginsenoside Re in ob/ob mice.
Academic Article Confirmed locus on chromosome 11p and candidate loci on 6q and 8p for the triglyceride and cholesterol traits of combined hyperlipidemia.
Academic Article Insulin gene mutations as a cause of permanent neonatal diabetes.
Academic Article Noninvasive monitoring of changes in pancreatic beta-cell mass by bioluminescent imaging in MIP-luc transgenic mice.
Academic Article Sustained expression of hepatocyte nuclear factor-6 leads to loss of pancreatic beta-cells by apoptosis.
Academic Article Insulin mutation screening in 1,044 patients with diabetes: mutations in the INS gene are a common cause of neonatal diabetes but a rare cause of diabetes diagnosed in childhood or adulthood.
Academic Article Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population.
Academic Article Subcellular recruitment by TSG118 and TSPYL implicates a role for zinc finger protein 106 in a novel developmental pathway.
Academic Article Association of the (AU)AT-rich element polymorphism in PPP1R3 with hormonal and metabolic features of polycystic ovary syndrome.
Academic Article The linkage and association of the gene encoding upstream stimulatory factor 1 with type 2 diabetes and metabolic syndrome in the Chinese population.
Academic Article From clinicogenetic studies of maturity-onset diabetes of the young to unraveling complex mechanisms of glucokinase regulation.
Academic Article Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance.
Academic Article Variation in the perilipin gene (PLIN) affects glucose and lipid metabolism in non-Hispanic white women with and without polycystic ovary syndrome.
Academic Article Common polymorphisms of calpain-10 are associated with abdominal obesity in subjects at high risk of type 2 diabetes.
Academic Article Obesity and hyperinsulinemia in a family with pancreatic agenesis and MODY caused by the IPF1 mutation Pro63fsX60.
Academic Article Calpain-10 is a component of the obesity-related quantitative trait locus Adip1.
Academic Article Neonatal diabetes mellitus: a model for personalized medicine.
Academic Article Seeing is believing: how the MIP-luc mouse can advance the field of islet transplantation and ß-cell regeneration.
Academic Article The cost-effectiveness of personalized genetic medicine: the case of genetic testing in neonatal diabetes.
Academic Article TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action.
Academic Article MODY: history, genetics, pathophysiology, and clinical decision making.
Academic Article Association of the KCNJ11 variant E23K with type 2 diabetes in Indo-Trinidadians.
Academic Article An in vivo cis-regulatory screen at the type 2 diabetes associated TCF7L2 locus identifies multiple tissue-specific enhancers.
Academic Article Characterization of Japanese families with early-onset type 2 (non-insulin dependent) diabetes mellitus and screening for mutations in the glucokinase and mitochondrial tRNA(Leu(UUR)) genes.
Academic Article Identification of microsatellite markers near the human ob gene and linkage studies in NIDDM-affected sib pairs.
Academic Article Identification of two novel amino acid polymorphisms in beta-cell/liver (GLUT2) glucose transporter in Japanese subjects.
Academic Article Splice variant of the somatostatin receptor 2 subtype, somatostatin receptor 2B, couples to adenylyl cyclase.
Academic Article Dinucleotide repeat polymorphism at D9S328E (EST hbc220).
Academic Article Human G-protein-coupled inwardly rectifying potassium channel (GIRK1) gene (KCNJ3): localization to chromosome 2 and identification of a simple tandem repeat polymorphism.
Academic Article Localization of the kappa opioid receptor gene to human chromosome band 8q11.2.
Academic Article Human thyroxine-binding globulin gene: complete sequence and transcriptional regulation.
Academic Article Human hexokinase II: localization of the polymorphic gene to chromosome 2.
Academic Article Core transcriptional regulatory circuitry in human hepatocytes.
Academic Article Assignment of the gastric inhibitory polypeptide receptor gene (GIPR) to chromosome bands 19q13.2-q13.3 by fluorescence in situ hybridization.
Academic Article Human type I pituitary adenylate cyclase activating polypeptide receptor (ADCYAP1R): localization to chromosome band 7p14 and integration into the cytogenetic, physical, and genetic map of chromosome 7.
Academic Article Localization of inositol trisphosphate receptor subtype 3 to insulin and somatostatin secretory granules and regulation of expression in islets and insulinoma cells.
Academic Article Gi alpha 3 and G(o) alpha selectively associate with the cloned somatostatin receptor subtype SSTR2.
Academic Article Mutation of an aspartate at residue 89 in somatostatin receptor subtype 2 prevents Na+ regulation of agonist binding but does not alter receptor-G protein association.
Academic Article Human fructose-1,6-bisphosphatase gene (FBP1): exon-intron organization, localization to chromosome bands 9q22.2-q22.3, and mutation screening in subjects with fructose-1,6-bisphosphatase deficiency.
Academic Article Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat.
Academic Article A molecular inventory of human pancreatic islets: sequence analysis of 1000 cDNA clones.
Academic Article No evidence for mutations in a putative beta-cell ATP-sensitive K+ channel subunit in MODY, NIDDM, or GDM.
Academic Article Clinical characteristics of subjects with a missense mutation in glucokinase.
Academic Article Localization of the gene encoding a neutral amino acid transporter-like protein to human chromosome band 19q13.3 and characterization of a simple sequence repeat DNA polymorphism.
Academic Article G protein-activated inwardly rectifying potassium channel (GIRK1/KGA) mRNA in adult rat heart and brain by in situ hybridization histochemistry.
Academic Article Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.
Academic Article Mutations in the glucokinase gene are not a major cause of late-onset type 2 (non-insulin-dependent) diabetes mellitus in Japanese subjects.
Academic Article Stimulation of tyrosine phosphatase and inhibition of cell proliferation by somatostatin analogues: mediation by human somatostatin receptor subtypes SSTR1 and SSTR2.
Academic Article Agonists and antagonists bind to different domains of the cloned kappa opioid receptor.
Academic Article Glucokinase: structural analysis of a protein involved in susceptibility to diabetes.
Academic Article Immunological detection of isoforms of the somatostatin receptor subtype, SSTR2.
Academic Article Dinucleotide repeat polymorphism in the NEC2 gene.
Academic Article Expression of calcium channel mRNAs in rat pancreatic islets and downregulation after glucose infusion.
Academic Article Structure and function of ASP, the human homolog of the mouse agouti gene.
Academic Article Linkage of Rieger syndrome to the region of the epidermal growth factor gene on chromosome 4.
Academic Article Assignment of the gene encoding the alpha 1 subunit of the neuroendocrine/brain-type calcium channel (CACNL1A2) to human chromosome 3, band p14.3.
Academic Article Alternative splicing of human inwardly rectifying K+ channel ROMK1 mRNA.
Academic Article Somatostatin receptors, an expanding gene family: cloning and functional characterization of human SSTR3, a protein coupled to adenylyl cyclase.
Academic Article The population association of glucokinase gene with type 2 (noninsulin-dependent) diabetes mellitus in Chinese.
Academic Article Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1.
Academic Article A single residue, aspartic acid 95, in the delta opioid receptor specifies selective high affinity agonist binding.
Academic Article Organization of the human GLUT2 (pancreatic beta-cell and hepatocyte) glucose transporter gene.
Academic Article Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes.
Academic Article A yeast artificial chromosome-based map of the region of chromosome 20 containing the diabetes-susceptibility gene, MODY1, and a myeloid leukemia related gene.
Academic Article A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2.
Academic Article Clinical and molecular genetics of neonatal diabetes due to mutations in the insulin gene.
Academic Article Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism.
Academic Article Exome sequencing and genetic testing for MODY.
Academic Article Genetic contribution of polymorphism of the GLUT1 and GLUT4 genes to the susceptibility to type 2 (non-insulin-dependent) diabetes mellitus in different populations.
Academic Article Identification of 14 new glucokinase mutations and description of the clinical profile of 42 MODY-2 families.
Academic Article Mutations in the hepatocyte nuclear factor-1alpha gene are a common cause of maturity-onset diabetes of the young in the U.K.
Academic Article Localization of human homeodomain transcription factor insulin promoter factor 1 (IPF1) to chromosome band 13q12.1.
Academic Article Cloning of rat KATP-2 channel and decreased expression in pancreatic islets of male Zucker diabetic fatty rats.
Academic Article The 31-cM region of chromosome 11 including the obesity gene tubby and ATP-sensitive potassium channel genes, SUR1 and Kir6.2, does not contain a major susceptibility locus for NIDDM in 127 non-Hispanic white affected sibships.
Academic Article Missense glucokinase mutation in maturity-onset diabetes of the young and mutation screening in late-onset diabetes.
Academic Article Mapping diabetes-susceptibility genes. Lessons learned from search for DNA marker for maturity-onset diabetes of the young.
Academic Article Variation in the calpain-10 gene affects blood glucose levels in the British population.
Academic Article Locus on chromosome 6p linked to elevated HDL cholesterol serum levels and to protection against premature atherosclerosis in a kindred with familial hypercholesterolemia.
Academic Article Organ alchemy: producing insulin in the liver.
Academic Article Linkage of calpain 10 to type 2 diabetes: the biological rationale.
Academic Article Abnormal insulin secretion, not insulin resistance, is the genetic or primary defect of MODY in the RW pedigree.
Academic Article 5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways.
Academic Article Identification of type 2 diabetes genes in Mexican Americans through genome-wide association studies.
Academic Article Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
Academic Article Linkage and association between insulin-dependent diabetes mellitus (IDDM) susceptibility and markers near the glucokinase gene on chromosome 7.
Academic Article Cloning of rat and mouse P2Y purinoceptors.
Academic Article Creation of an inositol 1,4,5-trisphosphate-sensitive Ca2+ store in secretory granules of insulin-producing cells.
Academic Article Regulation of expression of the human fructose transporter (GLUT5) by cyclic AMP.
Academic Article Molecular model of human beta-cell glucokinase built by analogy to the crystal structure of yeast hexokinase B.
Academic Article Type 2 (non-insulin-dependent) diabetes mellitus associated with a mutation of the glucokinase gene in a Japanese family.
Academic Article Sequence, tissue distribution, and functional characterization of the rat fructose transporter GLUT5.
Academic Article Cloning of a novel somatostatin receptor, SSTR3, coupled to adenylylcyclase.
Academic Article Dinucleotide repeat polymorphism in the human thyroid hormone receptor alpha gene (THRA1) on chromosome 17.
Academic Article Microsatellite polymorphism in the human platelet glycoprotein IIIa gene (GP3A) on chromosome 17.
Academic Article Human pancreatic beta-cell glucokinase: cDNA sequence and localization of the polymorphic gene to chromosome 7, band p 13.
Academic Article Dinucleotide repeat polymorphism at the human ribophorin II locus (RPN2) on chromosome 20q.
Academic Article Molecular biology of opioid receptors.
Academic Article Molecular properties of somatostatin receptors.
Academic Article The cloned kappa opioid receptor couples to an N-type calcium current in undifferentiated PC-12 cells.
Academic Article Localization of the glucagon receptor gene to human chromosome band 17q25.
Academic Article Classification and nomenclature of somatostatin receptors.
Academic Article Molecular mechanisms of agonist-induced desensitization of the cloned mouse kappa opioid receptor.
Academic Article Differential expression of messenger RNAs for somatostatin receptor subtypes SSTR1, SSTR2 and SSTR3 in adult rat brain: analysis by RNA blotting and in situ hybridization histochemistry.
Academic Article Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms.
Academic Article Molecular biology of somatostatin receptors.
Academic Article Characterization of cloned somatostatin receptors SSTR4 and SSTR5.
Academic Article Structure and function of mammalian facilitative sugar transporters.
Academic Article Cloned somatostatin receptors: identification of subtype-selective peptides and demonstration of high affinity binding of linear peptides.
Academic Article Molecular biology of somatostatin receptors.
Academic Article Molecular genetics of myeloid leukemia: identification of the commonly deleted segment of chromosome 20.
Academic Article Evolution of simple sequence repeats.
Academic Article Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation.
Academic Article Sexual partner networks in the transmission of sexually transmitted diseases. An analysis of gonorrhea cases in Sheffield, UK.
Academic Article Altered hepatic gene expression of enzymes involved in energy metabolism in the growth-retarded fetal rat.
Academic Article The length distribution of perfect dimer repetitive DNA is consistent with its evolution by an unbiased single-step mutation process.
Academic Article The advantage of sex in evolving yeast populations.
Academic Article A prospective social and molecular investigation of gonococcal transmission.
Academic Article The oligogenic view of adaptation.
Academic Article Enhancing pancreatic Beta-cell regeneration in vivo with pioglitazone and alogliptin.
Academic Article In vitro scan for enhancers at the TCF7L2 locus.
Academic Article Human somatostatin receptor genes: localization of SSTR5 to human chromosome 20p11.2.
Academic Article Molecular biology of somatostatin receptors.
Academic Article Cost-effectiveness of MODY genetic testing: translating genomic advances into practical health applications.
Academic Article Genetics and pathophysiology of neonatal diabetes mellitus.
Academic Article GSK-3ß function in bone regulates skeletal development, whole-body metabolism, and male life span.
Academic Article Effect of genetic variation in a Drosophila model of diabetes-associated misfolded human proinsulin.
Academic Article Sex and the spread of retrotransposon Ty3 in experimental populations of Saccharomyces cerevisiae.
Academic Article Genetic complexity in a Drosophila model of diabetes-associated misfolded human proinsulin.
Academic Article Association of a low-frequency variant in HNF1A with type 2 diabetes in a Latino population.
Academic Article Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
Academic Article Continued lessons from the INS gene: an intronic mutation causing diabetes through a novel mechanism.
Academic Article Genome-Wide Association Study of Staphylococcus aureus Carriage in a Community-Based Sample of Mexican-Americans in Starr County, Texas.
Academic Article Beyond type 2 diabetes, obesity and hypertension: an axis including sleep apnea, left ventricular hypertrophy, endothelial dysfunction, and aortic stiffness among Mexican Americans in Starr County, Texas.
Academic Article The genetic architecture of type 2 diabetes.
Academic Article Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms.
Academic Article Disturbance and diversity in experimental microcosms.
Academic Article Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans.
Academic Article A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk.
Academic Article Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees.
Academic Article Femtosecond laser desorption ionization mass spectrometry imaging and multivariate analysis of lipids in pancreatic tissue.
Academic Article A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes.
Academic Article Multiethnic Meta-Analysis Identifies RAI1 as a Possible Obstructive Sleep Apnea-related Quantitative Trait Locus in Men.
Academic Article Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
Academic Article Functionally oriented analysis of cardiometabolic traits in a trans-ethnic sample.
Concept Pulse Wave Analysis
Grant GENES FOR NON-INSULIN-DEPENDENT DIABETES MELLITUS
Grant MOLECULAR MECHANISMS/BETA CELL DYSFUNCTION IN DIABETES
Grant Diabetes Research and Training Center
Grant Diabetes Research and Training Center
Grant GENES RESPONSIBLE IN INSULIN-DEPENDENT DIABETES MELLITUS
Grant A Fly Model of Complex Protein Misfolding Disease
Grant Functional follow-up of the association between TCF7L2 and T2D
Grant Transcriptional Regulatory Networks in Pancreatic Islets
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